ROLE OF HYPERBARIC THERAPY IN
AUTISM SPECTRUM DISORDERS

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Hyperbaric therapy is a means to enhance oxygen delivery to ischemic tissues of the body. For details see Index to HBOT Files

Please understand that HBOT is a generic treatment procedure. It controls hypoxia and inflammation in any tissue, and also has wide ranging specific benefits as given below. These include:
  1. It reduces tissue swelling (oedema)
  2. The reduced swelling enables capillaries to open up to enhance microcirculation
  3. It promotes many chemicals to be released (Angio-genetic factors) that enhance new capillary growth from normal areas towards ischemic zones
  4. It acts like an "Internal Hydrogen-peroxide antiseptic" to kill microbes
  5. It enhances the oxygen dissolved in tissue fluid that is the ONLY source of direct oxygen supply to any tissue of the body including brain, as per Henry's law of Physics that states that pressure exerted on a water body is directly proportional to the solubility of a gas in water. Thus, once the blood / tissue fluid gets oxygen enriched, simple laws of diffusin does the rest to carry it from "Normal" perfused tissues to "Ischemic" low perfused tissues
Hyperbaric Oxygen Therapy, in addition to its well understood role of enhancing solubility of gas (Oxygen) under increased pressure inside the chamber to enhance tissue oxygenation, edema reduction, inflammation reduction and recovery of ischemic penumbra zone of injury, has been shown to have the following beneficial enhanced effects :
Mechanism of brain injury
HBOT was first used about a few centuries ago, and virtually predates modern allopathic medicine (SURPRISED?????). Lack of placebo controlled double blind randomised clinical trials have upheld its progress.
Yes, it is costly. So which patient will pay the Rs.1.5 lakh to standard commercial hospitals if he is told that he may get actual HBOT or a sham treatment? Will you?

To give an example: ibuoprofen works as a pain and inflammation remover in cases of Arthritis and traumatic pain in leg of a football player, as per a clinical study done. Do you still need a study to prove that it will also work in relieving inflammation and pain in a traumatic injury of the right elbow, and another one for the left elbow and another one for the back bone.......????

Do you want our opinion on your special need child ?

We, at FSMHP-UDAAN for the Disabled, are a team of doctors, therapists and psychologists who will work with the child, assessing him/her, using diagnostic and well as PROGNOSTIC scales. The medical wing will assess his physiology and biochemical parameters, micronutrient levels, allergy and toxicology profile, blood metal profiles, serum vitamin levels, and then guide the dietician to plan out a well balanced allergen free well tolerated diet suitable for a normal child of his/her sex, weight and age (DAN Protocol based). Certain specific genetic parameters will also need testing and remedial medical means adopted. All of these will be evidence based approach to the limit possible in India. After three months or more of this process, we will do a CT-cum-SPECT Fusion Scan of brain using dyes at an appropriate dose for small children. After analysing that scan, we suggest what degree of benefit may accrue from HBOT. In severe and evident cases of brain hypoxia, we may dispense with the CT-SPECT scan to reduce costs.

Just as in any class of 50 normal kids, someone becomes a lower division clerk while another becomes a high beaureacrat or very high ranking professional, similarly, different children will respond differently. About a quarter so improve remarkably, a little more than one third show good improvement, another quarter will show minor improvements, while the balance will not show any statistically significant improvement.

HBOT for brain recovery.

The Times of India Mumbai Edition, September 21, 2009; Section: Times City; page 7, had an article on HBOT usage in Autism, and had quoted a pediatric neurologist who said that a study showed that HBOT does not work in CP. This is a rypical example of a closed moind. He comment is based on erroneaous interpretation of that particular study, which has subsequently been shown to be a falsehood imposed on disabled chlildren and their families, to save Tax dollars by officialy denying them

The rate of neurodevelopment of motor activity in a CP child is measured by changes in the GMFM Scale, best assessed using a GMAE Estimator software, which is rarely found anywhere in India (UDAAN has been using it since 2003). This was the main tool used in the Collet study on HBOT in CP from Quebec, Canada, that the doctor was referring to, as published in the Lancet in 2001. That study clearly showed that when CP children are NOT TREATED, their GMFM score spontaneously improved at a rate of 0.1 per month, whereas when either HBOT at 1.75 Atmospheric pressure (ATA) with 100% oxygen was used or 1.3 Atmospheric pressure with ambient air was used, the GMFM change JUMPED to 1.0 or more per month: that is, a TEN FOLD Spontaneous jump. Is that a joke?

But that Pediatric Neurologist, not knowing the implications of GMAE and GMFM, could not appreciate that, and only went by the commentary repeated ad-nauseaum at every forum by Collet, who is neither a qualified doctor nor a HBOT therapist, but only a Government employed Pharmacist who used to do drug trials, who was thrust upon the team of genuine doctors, pediatricians and HBOT Therapists lead by Pierre Marois, to discredit the study so that Government would not have to re-imburse the money for HBOT in CP. Now that this trickery has been exposed, the state in Canada, where the study took place, has accorded recognition to HBOT as a reimbursible treatment for CP as have more than 16 states in USA.

I wonder how many in India are aware of this. Talk about a Frog-in-the-well attitude..

Some more References on HBOT in Autism

Jessada Chungpaibulpatana, http://www.vachiraphuket.go.th/hc/UserFiles/File/article/Hyperbaric_oxygen_therapy_in_thai_autistic_children.pdf
Dan Rossignol, http://www.biomedcentral.com/content/pdf/2045-9912-2-16.pdf G Heuser, http://www.healim.net/clinic3/images/hbot_ps/004.pdf
A El-Ansari, http://omicsonline.org/role-of-gut-brain-axis-in-the-aetiology-of-neurodevelopmental-disorders-with-reference-to-autism-2161-0495.S6-005.pdf